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Enzymes for Research, Diagnostic and Industrial Use

NS-398

Cat No.
CEI-0215
Description
NS-398 is a selective inhibitor of COX-2 with IC50 of 150 nM.
CAS No.
123653-11-2
Molecular Weight
314.36
Purity
>98%
Storage
2 years -20centigrade Powder
Targets
Cyclo-oxygenase 2
Molecular Formula
C13H18N2O5S
Chemical Name
N-[2-cyclohexyloxy-4-nitrophenyl] methanesulfonamide
Solubility
DMSO 25 mg/mL,Water
In vitro
NS-398 (N-[2-cyclohexyloxy-4-nitrophenyl] methanesulfonamide) is an non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. NS-398 can selectively inhibits cyclooxygenase-2 (COX-2) with IC50 of 150 nM. The IC50 values for human recombinant COX-1 and COX-2 are 75µM and 1.77 µM, respectively.
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