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Enzymes for Research, Diagnostic and Industrial Use

NVP-BSK805

Cat No.
CEI-1133
Description
NVP-BSK805 is a potent and selective quinoxaline JAK2 inhibitor with IC50 of 0.48, 0.56 and 0.58 nM for JAK2 JH1, FL JAK V617F and FL JAK2 wt, respectively.
Abbr
NVP-BSK805(JAK2)
Alias
JTK10, THCYT3
CAS No.
1092499-93-8
Molecular Weight
563.47
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
JTK10, THCYT3
Targets
JAK2 JH1, FL JAK V617F, FL JAK2 wt
Molecular Formula
C27H28F2N6O.2HCl
Chemical Name
8-(3,5-difluoro-4-(morpholinomethyl)phenyl)-2-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxaline dihydrochloride
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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