Description
Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).
Abbr
GLA, Native (Aspergillus niger)
Applications
High purity alpha-Galactosidase (A. niger) for use in research, biochemical enzyme assays and in vitro diagnostic analysis.
Form
In 3.2 M ammonium sulphate.
Enzyme Commission Number
EC 3.2.1.22
Unit Definition
One Unit of activity is the amount of enzyme required to release one micromole of product (e.g. p-nitrophenyl) per min at pH 4.5 and 40°C.
Thermal stability
Unstable above 60°C
Stability
> 4 years at 4°C.
Storage
Stored at 4°C. On dissolution in buffer, the enzyme should be stored in the frozen state in a polypropylene container between use. We recommend the addition of BSA (0.5 mg/mL) to all dilution buffers to improve stability of the enzyme.
Synonyms
Alpha-Galactosidase; Galactosidase; EC 3.2.1.22; GLA; GALA; melibiase; α-D-galactosidase; α-galactosidase A; α-galactoside galactohydrolase