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Native Bacillus cereus Sphingomyelinase

Cat No.
NATE-0672
Description
Sphingomyelin phosphodiesterase is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.
Abbr
SMase, Native (Bacillus cereus)
Alias
SMase
Source
Bacillus cereus
Applications
Sphingomyelinase has been used in a study to assess the interaction of actin with the HIV-1 accessory protein Nef. Sphingomyelinase has also been used in a study to investigate X-ray scattering as a quality-control tool for liposomal drug-delivery systems.
Form
Type I, buffered aqueous glycerol solution, Solution in 50% glycerol containing 50 mM Tris-HCl, pH 7.5; Type II, Lyophilized powder containing potassium phosphate buffer salts and stabilizer.
Enzyme Commission Number
EC 3.1.4.12
Activity
> 100 units/mg protein
CAS No.
9031-54-3
Unit Definition
One unit will hydrolyze 1.0 μmole of TNPAL-sphingomyelin per min at pH 7.4 at 37°C.
Storage
2-8°C
Synonyms
Sphingomyelin phosphodiesterase; EC 3.1.4.12; neutral sphingomyelinase; 9031-54-3; sphingomyelin cholinephosphohydrolase; sphingomyelinase; SMase
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Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogNATE-0673
EC No.EC 3.1.4.12
CAS No.9031-54-3
SourceStaphylococcus aureus
CatalogNATE-1160
EC No.EC 3.1.4.12
CAS No.9031-54-3
SourceStreptomyces sp.
CatalogEXWM-3712
EC No.EC 3.1.4.12
CAS No.9031-54-3
Source
Realted Service
Realted Protocols
SPHINGOMYELINASE -Enzymatic Assay Protocol
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