Description
Prepared from Bovine Factor IX by activation with Bovine Factor Xla, this Bovine Factor Xla is removed after activation. Complete activation is observed by SDS-PAGE. The Factor Xla activates FIX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce factor IXaβ.
Abbr
Factor IXa β, Native (Bovine)
Molecular Weight
43.9 kDa
Buffer
20 mM Tris-HCl/ 0.1 M NaCl/ pH 7.4
Synonyms
Bovine Factor IXa Beta; Factor IXa Beta; Factor Ixa