Description
β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption.
Abbr
GUSB, Native (Bovine)
Applications
β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression.
Enzyme Commission Number
EC 3.2.1.31
Activity
Type B-10, ~10,000 units/mg solid; Type B-1, > 1,000,000 units/g solid; Type B-3, > 2,000,000 units/g solid
Unit Definition
One unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37°C at pH 5.0 (30 min assay).
Pathway
Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem (from KEGG) Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem (from KEGG) Chondroitin sulfate degradation, organism-specific biosystem (from KEGG)
Function
AnxA6 is a novel receptor that mediates the endocytosis of bovine beta-glucuronidase.
Synonyms
β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB
