Description
A lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NADH to NAD+ and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another.
Abbr
LDH, Native (Thermophillic bacteria)
Source
Thermophillic bacteria
Applications
Diagnostic test and biosensors; NADH recycling. This enzyme is a potential candidate for biocatalysis, suitable for pharmaceutical development / manufacturing.
Enzyme Commission Number
EC 1.1.1.27
Unit Definition
One unit is defined as the amount of enzyme oxidizing 1μmol of NADH per 1 minute (ε340 = 6.22 mM-1 cm-1).
Thermal stability
~100% stability after 1 hour at 70°C
Buffer
20 mM Tris-HCl (pH 8.0)
Synonyms
Lactate dehydrogenase; EC 1.1.1.27; LDH; LD
