Description
Creatine Kinase is an enzyme present in muscle, brain, and other tissues of vertebrates that catalyzes the reversible conversion of ADP and phosphocreatine into ATP and creatine.
Elevated levels of creatine phosphokinase indicates possible Brain injury or stroke, convulsions, delirium tremens, Dermatomyositis or polymyositis, electric shock, Heart attack, Inflammation of the heart muscle (myocarditis), Lung tissue death (pulmonary infarction), Muscular dystrophies and Myopathy.
Appearance
Reddish to pink lyophilized powder
Form
Lyophilized from tris acetate, DTT and EDTA, pH: 7.0
Enzyme Commission Number
EC 2.7.3.2
Contaminants
ALP: < 0.01%
LDH: < 0.01%
ALT/GPT: < 0.01%
GOT/AST: < 1%
Ammonia: < 0.01 micromole/mg
Unit Definition
One unit catalyzes the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C.
Synonyms
EC 2.7.3.2; ATP:creatine phosphotransferase; CK; CPK; creatine phosphokinase; creatine phosphotransferase; phosphocreatine kinase; adenosine triphosphate-creatine transphosphorylase; 9001-15-4
