Description
Protein Phosphatase 1 is a growth factor stimulated, divalent cation-independent serine/threonine protein phosphatase involved in regulating numerous cellular processes such as glycogen metabolism, mitosis, and meiosis.
Abbr
PP1C, Native (Rabbit)
Applications
Protein phosphatase-1C has been used in a study to investigate why two metabolites of microcystin-LR glutathione conjugate and microcystin-cysteine conjugate, as well as microcystin-RR are less toxic than microcystin-LR.
Product Overview
Protein phosphatase 1C (PP1C) is expressed in the dendrites of retinal bipolar cells where it was found to bind to group I metabotropic glutamate receptors indicating a function for PP1C in glutamatergic signal transduction. >90% (SDS-PAGE), buffered aqueous glycerol solution
Form
buffered aqueous glycerol solution
Activity
> 1500 units/mg protein
Unit Definition
One unit will release 1.0 nanomole of phosphate from 32P-labeled phosphorylase per min at pH 7.0 at 30°C.
Buffer
Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol.
Synonyms
Protein Phosphatase 1C; PP1C
