Description
Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions.
Abbr
Neuraminidase, Recombinant
Form
White powder, lyophilized
Enzyme Commission Number
EC 3.2.1.18
Molecular Weight
About 58kDa (SDS-PAGE detection)
Purity
90% (SDS-PAGE test)
Unit Definition
One unit will convert 1µmol of saliva to hydrolysis per min at pH6.5 at 37°C.
Storage
4°C,store at -20°C for long-term preservation
Buffer
50mM phosphate buffer, pH6.8
Synonyms
neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6
Formulation
0.05 M Tris base and 0.5 M NaCl (before lyophilizing)
