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Nocodazole
Cat No.
CEI-0564
Description
A microtubule inhibitor; inhibits mitosis. Disrupts microtubules by binding to β‑tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Arrests the cell cycle at G2/M phase. Also inhibits autophagosome-lysosome fusion.
Appearance
White to off-white solid
Product Overview
A microtubule inhibitor
CAS No.
31430-18-9
Molecular Weight
391.51
Purity
>98% by NMR
Storage
-20 centigrade
Targets
Microtubule
Molecular Formula
C 14 H 11 N 3 O 3 S
Chemical Name
5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester
Solubility
DMSO (>30 mg/ml) and Ethanol
Shipping Conditions
Gel pack
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