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Enzymes for Research, Diagnostic and Industrial Use

PF-5274857

Cat No.
CEI-1165
Description
PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.
Abbr
PF-5274857(SMO)
Alias
FZD11, Gx, SMOH
CAS No.
1373615-35-0
Molecular Weight
436.96
Purity
> 95%
Storage
4 centigrade
Synonyms
FZD11, Gx, SMOH
Targets
Smoothened (Smo)
IC50
5.8 nM
Molecular Formula
C20H25ClN4O3S
Chemical Name
5'-chloro-3,5-dimethyl-2'-{4-[3-(methylsulfonyl)propanoyl]piperazin-1-yl}-2,4'-bipyridine
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