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PF-8380

Cat No.
CEI-1477
Description
PF-8380 is a potent and specific inhibitor of autotaxin with an IC50 value of 2.8 nM in isolated enzyme assay.
Product Overview
PF-8380 is a specific and potent inhibitor of Autotaxin (ATX) with an IC50 value of 2.8 nM. Autotaxin (ATX) is a secreted enzyme having lysophospholipase D activity
CAS No.
1144035-53-9
Molecular Weight
478.33
Purity
0.9941
Storage
Store at -20°C
Synonyms
PF 8380; PF8380
Targets
Autotaxin
IC50
2.8 nM
Molecular Formula
C22H21Cl2N3O5
Chemical Name
3,5-dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate
Solubility
Soluble in DMSO > 10 mM
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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