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Enzymes for Research, Diagnostic and Industrial Use

PFI-1

Cat No.
CEI-0408
Description
PFI-1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. In an AlphaScreen assay it has been shown to inhibit BRD2 bromodomain 2 and BRD4 bromodomain 1 with IC50 values of 98 nM and 0.22 μM, respectively.
Appearance
Crystalline solid
Product Overview
A potent BET bromodomain inhibitor
CAS No.
1403764-72-6
Molecular Weight
358.48
Purity
>98%
Storage
-20 centigrade
Targets
BRD2, BRD4
Molecular Formula
C 16 H 17 N 3 O 4 S
Chemical Name
2-​Methoxy-​N-​(3-​methyl-​2-​oxo-​1,​2,​3,​4-​tetrahydroquinazolin-​6-​yl)benzenesulfonamide
Solubility
DMSO
Shipping Conditions
Gel Pack
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