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PJ-34 hydrochloride

Cat No.
CEI-0553
Description
A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells.
Appearance
White to off-white solid
Product Overview
A potent Leukocyte activation pathways inhibitor
CAS No.
344458-15-7
Molecular Weight
490.5
Purity
>98% by HPLC
Storage
-20 centigrade
Targets
Leukocyte activation pathways
Molecular Formula
C 17 H 17 N 3 O 2 .HCl
Chemical Name
N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride
Solubility
DMSO (~ 10 mg/ml)
Shipping Conditions
Gel pack
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