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Enzymes for Research, Diagnostic and Industrial Use

phosphohistidine phosphatase

Cat No.
EXWM-4751
Description
This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- and tele-nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most). The substrate specificity depends on the amino acid sequence or structural context of the phosphohistidine in a phosphoprotein. The enzyme is also active on free phosphoramidate and peptide-bound phospholysine.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
PHPT1 (gene name); protein histidine phosphatase; PHP
Reaction
a [protein]-N-phospho-L-histidine + H2O = a [protein]-L-histidine + phosphate
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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