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Enzymes for Research, Diagnostic and Industrial Use

R1487

Cat No.
CEI-1116
Description
R1487 is a p38 MAP kinase inhibitor with an IC50 value of 10nM. May have potential as a treatment for inflammatory diseases such as rheumatoid arthritis.
Abbr
R1487(MAPK14)
Alias
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Product Overview
p38 MAP kinase inhibitor
CAS No.
449808-64-4
Molecular Weight
424.83
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Targets
MAPK (p38MAP)
Molecular Formula
C19H18F2N4O3.HCl
Chemical Name
6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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