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ribonuclease III

Cat No.
EXWM-3591
Description
This is an endoribonuclease that cleaves double-stranded RNA molecules. The cleavage can be either a single-stranded nick or double-stranded break in the RNA, depending in part upon the degree of base-pairing in the region of the cleavage site. Specificity is conferred by negative determinants, i.e., the presence of certain Watson-Crick base-pairs at specific positions that strongly inhibit cleavage. RNase III is involved in both rRNA processing and mRNA processing and decay.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
9073-62-5
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
RNase III; ribonuclease 3
Reaction
Endonucleolytic cleavage to a 5'-phosphomonoester
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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