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S-(5'-Adenosyl)-L-Methionine Iodide

Cat No.
COEC-099
Description
S-(5'-Adenosyl)-L-Methionine Iodideis methyl donor and cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). S-(5'-Adenosyl)-L-methionine (SAM, AdoMet) is used as a primary methyl donor molecule in mammalian cell culture and the first step metabolite in methionine biosynthesis. Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
Applications
Cofactor for enzyme-catalyzed methylations
Appearance
Powder
Form
Solid
CAS No.
3493-13-8
Molecular Weight
526.35
Purity
≥80%
Synonyms
AdoMet; SAM
Molecular Formula
C15H23IN6O5S
Solubility
Soluble in water (100 mg/ml).
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