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Enzymes for Research, Diagnostic and Industrial Use

SD-06

Cat No.
CEI-1107
Description
SD-06 is a p38 MAP kinase inhibitor. It inhibits p38α with an IC50 value of 170nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).
Abbr
SD-06(MAPK14)
Alias
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Product Overview
p38 MAP kinase inhibitor
CAS No.
271576-80-8
Molecular Weight
397.86
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha
Targets
MAPK (p38MAP)
Molecular Formula
C20H20ClN5O2
Chemical Name
1-(4-(5-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-3-yl)piperidin-1-yl)-2-hydroxyethanone
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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