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Enzymes for Research, Diagnostic and Industrial Use

SIRT2 Inhibitor, B2

Cat No.
CEI-0653
Description
Cell-permeable. A Sirtuin 2 (SIRT2) inhibitor (IC50 = 35 µM). Promotes inclusion formation in cellular models of both Huntington’s disease and Parkinson’s disease. Prevents huntingtin-mediated proteasome dysfunction and reduces α-synuclein-mediated toxicity.
Appearance
White to off-white solid
Product Overview
A potent SIRT2 inhibitor
CAS No.
115687-05-3
Molecular Weight
223.3
Purity
>98%
Storage
-20 centigrade
Targets
SIRT2
Molecular Formula
C 21 H 17 CIN 4 O 3
Chemical Name
5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, CPNQ
Solubility
DMSO (20 mg/ml) or EtOH (20 mg/ml)
Shipping Conditions
Gel pack
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