Products

Enzymes for Research, Diagnostic and Industrial Use

SR3677

Cat No.
CEI-1112
Description
SR3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM in enzyme and cell based assays. It displayed an off-target hit rate of 1.4% against 353 other kinases and only inhibited 3 out of a panel of 70 non-kinase enzymes and receptors in profiling studies.
Abbr
SR3677(ROCK2)
Alias
ROCK-II
Product Overview
ROCK-II inhibitor
CAS No.
1072959-67-1
Molecular Weight
408.45
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
ROCK-II
Targets
ROCK-II
IC50
3 nM
Molecular Formula
C22H24N4O4
Chemical Name
N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Download Datasheet:



Inquiry
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: