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Enzymes for Research, Diagnostic and Industrial Use

SU-5402

Cat No.
CEI-1113
Description
SU-5402 is a potent and selective inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1 (IC50 values of 20 and 30 nM, respectively). Also inhibits PDGFRβ and EGFR with IC50 values of 510 nM and > 100 μM, respectively.
Abbr
SU-5402(KDR, FGFR1, PDGFRB, EGFR)
Alias
CD309, FLK1, VEGFR, VEGFR2
Product Overview
inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1
CAS No.
215543-92-3
Molecular Weight
296.32
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
CD309, FLK1, VEGFR, VEGFR2
Targets
VEGFR2, FGFR1, PDGFRβ, EGFR
IC50
20nM, 30 nM, 510 nM,> 100 μM
Molecular Formula
C17H16N2O3
Chemical Name
3-(4-methyl-2-((Z)-(2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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