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Salermide

Cat No.
CEI-0650
Description
Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through reactivation of proapoptotic genes epigenetically repressed exclusively in cancer cells by SIRT1
Appearance
Coloreless solid
Product Overview
A SIRT1 and SIRT2 inhibitor
CAS No.
1105698-15-4
Molecular Weight
650.76
Purity
>99%
Storage
-20 centigrade
Targets
SIRT1, SIRT2
Molecular Formula
C₂₆H₂₂N₂O₂
Chemical Name
N-​[3-​[[(2-​hydroxy-​1-​naphthalenyl)methylene]amino]phenyl]-​a-​methyl-​benzeneacetamide
Solubility
DMSO or 100% EtOH
Shipping Conditions
RT
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