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single-stranded DNA cytosine deaminase

Cat No.
EXWM-4566
Description
The enzyme exclusively catalyses deamination of cytosine in single-stranded DNA. It preferentially deaminates five-nucleotide bubbles. The optimal target consists of a single-stranded NWRCN motif (W = A or T, R = A or G). The enzyme initiates antibody diversification processes by deaminating immunoglobulin sequences.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
AID; activation-induced deaminase; AICDA (gene name); activation-induced cytidine deaminase
Reaction
cytosine in single-stranded DNA + H2O = uracil in single-stranded DNA + NH3
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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