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Enzymes for Research, Diagnostic and Industrial Use

Sphingosine Kinase Inhibitor, SKI-I

Cat No.
CEI-0667
Description
Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
Appearance
Off-white solid
Product Overview
A non-lipid sphingosine kinase (SK) inhibitor
CAS No.
306301-68-8
Molecular Weight
306.12
Purity
>98% by NMR
Storage
-20 centigrade
Targets
SPHK1
Molecular Formula
C 25 H 18 N 4 O 2
Chemical Name
5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Solubility
DMSO (10 mg/ml) or EtOH (1 mg/ml)
Shipping Conditions
Gel pack
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