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Enzymes for Research, Diagnostic and Industrial Use

TAK-700 (Orteronel)

Cat No.
CEI-0232
Description
TAK-700 (Orteronel)
CAS No.
566939-85-3
Molecular Weight
307.35
Purity
>99%
Storage
2 years at -20 centigrade
Targets
CYP17
Molecular Formula
C18H17N3O2
Solubility
No
In vitro
TAK-700 is a non-steroidal imidazole inhibitor and TAK-700 can inhibit CYP17 with IC50 of 28 nM. TAK-700 is a selective inhibitor for CYP17 over 11beta-hydroxylase by an impressive 260-fold. TAK-700 can reduce testosterone and DHEA levels.
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