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TAPI-0

Cat No.
CEI-0679
Description
Inhibitor of TNF-α processing (IC50 = 100 nM). Inhibits TACE (ADAM17) and other metalloproteases with Ki (nM) values of 8.8, 17, 6, 68, 0.5 and 0.2 for TACE, MDC9 (ADAM9), MMP-1, MMP-3, MMP-9 and MMP-13, respectively.
Alias
TNF protease inhibitor-0; C1
Appearance
White solid
Product Overview
An inhibitor of TNF-α processing
CAS No.
143457-40-3
Molecular Weight
222.24
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
TNF protease inhibitor-0; C1
Targets
TNF
Molecular Formula
C 24 H 32 N 4 O 5
Chemical Name
N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide
Solubility
DMSO(75 mM) or Ethanol (50 mM)
Shipping Conditions
Gel pack
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