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tRNA (cytosine38-C5)-methyltransferase
Cat No.
EXWM-1805
Description
The eukaryotic enzyme catalyses methylation of cytosine38 in the anti-codon loop of tRNAAsp(GTC), tRNAVal(AAC) and tRNAGly(GCC). Methylation by Dnmt2 protects tRNAs against stress-induced cleavage by ribonuclease.
Form
Liquid or lyophilized powder
Enzyme Commission Number
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
Synonyms
hDNMT2 (gene name); DNMT2 (gene name); TRDMT1 (gene name)
Reaction
S-adenosyl-L-methionine + cytosine38 in tRNA = S-adenosyl-L-homocysteine + 5-methylcytosine38 in tRNA
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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