Products

Enzymes for Research, Diagnostic and Industrial Use

TWS119

Cat No.
CEI-0097
Description
TWS119
CAS No.
601514-19-6
Molecular Weight
318.33
Purity
>99%
Storage
2 years at -20 centigrade
Targets
GSK-3beta
Molecular Formula
C18H14N4O2
Solubility
No
In vitro
TWS119, a 4,6-disubstituted pyrrolopyrimidine that can induce neurogenesis in murine ESCs. TWS119 can reduce beta-catenin phosphorylation and induce nuclear translocation of beta-catenin.TWS119 also elevate glutamine synthetase production, impede synthesis of alpha-smooth muscle actin and Wnt5a with promoting the expression of glial fibrillary acidic protein, Wnt10b, and paired-like homeodomain transcription factor 2c. Abeta(1-42) can be effectively prevented by treatment with the GSK-3beta inhibitor, TWS119, thereby implicating GSK-3beta kinase activity in this pathogenic cascade.
Download Datasheet:



Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0758
EC No.
CAS No.
Source
CatalogCEI-0759
EC No.
CAS No.
Source
CatalogCEI-0760
EC No.
CAS No.
Source
CatalogCEI-0761
EC No.
CAS No.62673-69-2
Source
+ See More >>
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: