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Teniposide

Cat No.
CEI-0365
Description
Teniposide is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL). It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA-protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DNA.
Alias
Vumon
CAS No.
29767-20-2
Molecular Weight
656.65
Purity
>99%
Storage
2 years at -20 centigrade
Synonyms
Vumon
Targets
Topoisomerase II
Molecular Formula
C32H32O13S
Solubility
DMSO 40 mg/mL, Water
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