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Tofacitinib (CP-690550,Tasocitinib)

Cat No.
CEI-1070
Description
Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent versus JAK2 and JAK1. Phase 3.
Abbr
Tofacitinib (CP-690550, Tasocitinib)(JAK3)
Alias
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
CAS No.
477600-75-2
Molecular Weight
312.37
Purity
0.9966
Storage
2 years -20 centigrade Powder 2 weeks4centigradein DMSO 6 months-80centigradein DMSO
Synonyms
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Targets
JAK3
IC50
1 nM
Molecular Formula
C16H20N6O
Chemical Name
3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Solubility
DMSO 63 mg/mL
Water <1 mg/mL
Ethanol <1 mg/mL
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