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tropinone reductase I

Cat No.
EXWM-0110
Description
Also oxidizes other tropan-3α-ols, but not the corresponding β-derivatives. This enzyme along with EC 1.1.1.236, tropinone reductase II, represents a branch point in tropane alkaloid metabolism.Tropine (the product of EC 1.1.1.206) is incorporated into hyoscyamine and scopolamine whereas pseudotropine (the product of EC 1.1.1.236) is the first specific metabolite on the pathway to the calystegines. Both enzymes are always found together in any given tropane-alkaloid-producing species, have a common substrate, tropinone, and are strictly stereospecific.
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
118390-87-7
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
tropine dehydrogenase; tropinone reductase (ambiguous); TR-I
Reaction
tropine + NADP+ = tropinone + NADPH + H+
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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