UDP-Glc 4-epimerase from E. coli K12, Recombinant

Cat No.

NATE-1498

Description

The enzyme UDP-glucose 4-epimerase (EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity.

Abbr

GalE, Recombinant (E. coli K12)

Source

E. coli

Species

E. coli K12

Enzyme Commission Number

EC 5.1.3.2

CAS No.

9032-89-7

Molecular Weight

40 kDa

Purity

min 95% by SDS-PAGE

Unit Definition

One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol of UDP-Gal from UDP-Glc per minute at 37 °C.

Synonyms

Galactowaldenase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; Uridine diphospho-galactose-4-epimerase; UDP-glucose 4-epimerase; EC 5.1.3.2; UDP-galactose 4-epimerase; GALE

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