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Vinblastine Sulfate

Cat No.
CEI-0563
Description
A plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule assembly and causes aberrant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent.
Alias
Vincaleukoblastine sulfate salt; VLB
Appearance
White solid
Product Overview
A tubulin polymerrization inhibitor
CAS No.
143-67-9
Molecular Weight
271.27
Purity
>98% by HPLC
Storage
RT
Synonyms
Vincaleukoblastine sulfate salt; VLB
Targets
MGMT
Molecular Formula
C₄₆H₅₈N₄O₉S.H₂SO₄
Solubility
DMSO (100 mM)
Shipping Conditions
RT
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