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YM201636

Cat No.
CEI-0094
Description
YM201636 potently inhibits mammalian PIKfyve with an IC50 of 33 nM but not yeast orthologue Fab1 with an IC50 of >5 uM, exhibiting around 100-fold selectivity for PtdIns3P p110-alpha with an IC50 of 3 uM.
CAS No.
371942-69-7
Molecular Weight
467.48
Purity
>99%
Storage
2 years at -20 centigrade
Targets
PI3K
Molecular Formula
C25H21N7O3
Chemical Name
3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3,2:4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-
Solubility
DMSO 35 mg/mL,Water
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