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CMA1

Official Full Name
CMA1
Background
Chymases are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis. Because of its role in inflammation it has been investigated as a target in the treatment of asthma.
Synonyms
mast cell protease I; skeletal muscle protease; skin chymotryptic proteinase; mast cell serine proteinase, chymase; skeletal muscle (SK) protease; chymase; EC 3.4.21.39; 97501-92-3

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4133
ProductNamechymase
EC No.EC 3.4.21.39
CAS No.97501-92-3
Source
CatalogNATE-0817
EC No.EC 3.4.21.39
CAS No.97501-92-3
SourcePichia pastoris

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