Official Full Name
Endoglycosidase S2
Background
EndoS2 is an endoglycosidase which hydrolyzes N-glycan moieties on the Fc-part of IgGs including high mannose and bisected glycans. It has high specificity for human IgGs from all subclasses and many other species. It has also been reported to hydrolyze glycan moieties from alpha-1-acid glycoprotein. The enzyme can be an effective tool by minimizing side effects in various immunoassays caused by complement binding or cross-reactivity. Rapid and mild reaction conditions ensure minimized risk for sample prep-induced modifications.
Synonyms
GlycINATOR; EndoS2
