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PP1A

Official Full Name
PP1A
Background
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene. The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
PPP1CA; protein phosphatase 1; PP-1A; PP1A; PP1alpha; PPP1A

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogNATE-1243
EC No.
CAS No.
SourceE.coli
CatalogNATE-0614
EC No.
CAS No.
SourceE. coli

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