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Thymidine Phosphorylase

Official Full Name
Thymidine Phosphorylase
Background
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.
Synonyms
thymidine phosphorylase; pyrimidine phosphorylase; thymidine-orthophosphate deoxyribosyltransferase; animal growth regulators, blood platelet-derived endothelial cell growth factors; blood platelet-derived endothelial cell growth factor; deoxythymidine phosphorylase; gliostatins; pyrimidine deoxynucleoside phosphorylase; thymidine:phosphate deoxy-D-ribosyltransferase; EC 2.4.2.4; 9030-23-3

Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-2668
EC No.EC 2.4.2.4
CAS No.9030-23-3
Source
CatalogNATE-0703
EC No.EC 2.4.2.4
CAS No.9030-23-3
SourceE. coli
Related Services
Related Protocols
thymidine phosphorylase -Enzymatic Assay Protocol
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