A plant and fungal toxin, 3-nitropropionic acid acts as an irreversible inactivator of succinate dehydrogenase. Selectively inhibits succinic dehydrogenase complex (Complex II) in the mitochondrial electron transport chain. Also shown to cause brain lesions similar to those of Huntington′s disease.
Alias
3-NP
Appearance
Orange solid
Product Overview
An irreversible inactivator of succinate dehydrogenase.