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680C91

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Cat No.

CEI-0687

Description

Cell-permeable. A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO, Ki = 51 nM.) Tryptophan is metabolized to the endogenous AHR ligand by TDO which may be inhibited by 680C91. Active in vivo.

Appearance

White to off-white solid

Product Overview

A potent and selective tryptophan 2,3-dioxygenase (TDO) inhibitor

CAS No.

163239-22-3

Molecular Weight

228.24

Purity

>98% by HPLC

Storage

-20 centigrade

Targets

TDO2

Molecular Formula

C 15 H 11 FN 2

Chemical Name

6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole

Solubility

DMSO (50 mg/ml)

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