Products

Enzymes for Research, Diagnostic and Industrial Use

HIV Protease Mutant, Recombinant

Cat No.
NATE-0344
Description
HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIV’s ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research.
Abbr
HIV Protease, Recombinant
Alias
HIV-1 protease
Source
E. coli
Package
100 unit vial containing > 100ug protein
Form
Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol.
Enzyme Commission Number
EC 3.4.23.16
CAS No.
144114-21-6
Molecular Weight
mol wt ~10.8 kDa
Unit Definition
One unit of HIV protease will cleave 1picomole per minute of the substrate Abz-Ala-Arg-Val-Nle-Tyr (NO2)-Glu-Ala-Nle-NH2 at 37°C.
Storage
−70°C
Warnings
Bioengineered to resist autoproteolysis, resulting in an enzyme with improved stability and substantially higher activity levels over extended time periods to conduct kinetic assays. The enzyme includes the most commonlyeccurring background polymorphism that aids in the drug resistance profile.
Synonyms
human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16
Download Datasheet:


“HIV Protease” Total Products Page

Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-4253
EC No.EC 3.4.23.16
CAS No.144114-21-6
Source
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCSUB-0318
EC No.
CAS No.
Source
CatalogCSUB-0319
EC No.
CAS No.
Source
CatalogCSUB-0320
EC No.
CAS No.
Source
CatalogCSUB-0321
EC No.
CAS No.
Source
+ See More >>
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: