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Enzymes for Research, Diagnostic and Industrial Use

Native Human Aspartate Aminotransferase

Cat No.
NATE-0088
Description
Aspartate Aminotransferase (AST), also known as Glutamate Oxaloacetate Transaminase (GOT), is a pyridoxal phosphate-dependant enzyme which exists in two isoenzymes; mitochondrial and cytosolic forms. The AST enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. In hepatic disease, serum levels are used to assess liver necrosis and for determining prognosis. In patients with acute Myocardial infarction, measurement of AST isoenzymes provides diagnostic information that differs from that obtained by determination of other marker proteins. Creative Enzymes products are not intended for use in pharmaceutical applications.
Abbr
GOT, Native (Human)
Alias
AST; GOT
Source
Human Cardiac Tissue
Species
Human
Applications
Research Life Science ELISA Assay Clinical Chemistry
Enzyme Commission Number
EC 2.6.1.1
Activity
>50U/ml
CAS No.
9000-97-9
Storage
-20°C
Buffer
Human Cardiac Tissue
Synonyms
EC 2.6.1.1; glutamic-oxaloacetic transaminase; glutamic-aspartic transaminase; transaminase A; AAT; AspT; 2-oxoglutaRate-glutamate aminotransferase; aspartate α-ketoglutaRate transaminase; aspartate aminotransferase; aspartate-2-oxoglutaRate transaminase; aspartic acid aminotransferase; aspartic aminotransferase; aspartyl aminotransferase; AST; glutamate-oxalacetate aminotransferase; glutamate-oxalate transaminase; glutamic-aspartic aminotransferase; glutamic-oxalacetic transaminase; glutamic oxalic transaminase; GOT (enzyme); L-aspartate transaminase; L-aspartate-α-ketoglutaRate transaminase; L-aspartate-2-ketoglutaRate aminotransferase; L-aspartate-2-oxoglutaRate aminotransferase; L-aspartate-2-oxoglutaRate-transaminase; L-aspartic aminotransferase; oxaloacetate-aspartate aminotransferase; oxaloacetate transferase; aspartate:2-oxoglutaRate aminotransferase; glutamate oxaloacetate transaminase; 9000-97-9
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Realted Products
Catalog
ProductName
EC No.
CAS No.
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Price
CatalogNATE-0312
EC No.EC 2.6.1.1
CAS No.9000-97-9
SourcePorcine heart
CatalogNATE-0950
EC No.EC 2.6.1.1
CAS No.9000-97-9
SourceHuman Heart
CatalogNATE-0951
EC No.EC 2.6.1.1
CAS No.9000-97-9
SourceHuman Liver
CatalogNATE-1017
EC No.EC 2.6.1.1
CAS No.9000-97-9
SourceE. coli
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