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TAPI-0

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Cat No.

CEI-0679

Description

Inhibitor of TNF-α processing (IC50 = 100 nM). Inhibits TACE (ADAM17) and other metalloproteases with Ki (nM) values of 8.8, 17, 6, 68, 0.5 and 0.2 for TACE, MDC9 (ADAM9), MMP-1, MMP-3, MMP-9 and MMP-13, respectively.

Alias

TNF protease inhibitor-0; C1

Appearance

White solid

Product Overview

An inhibitor of TNF-α processing

CAS No.

143457-40-3

Molecular Weight

222.24

Purity

>98% by HPLC

Storage

-20 centigrade

Synonyms

TNF protease inhibitor-0; C1

Targets

TNF

Molecular Formula

C 24 H 32 N 4 O 5

Chemical Name

N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide

Solubility

DMSO(75 mM) or Ethanol (50 mM)

Shipping Conditions

Gel pack