Native Human Prostatic Acid Phosphatase

Cat No.

NATE-0505

Description

Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels.

Abbr

PAP, Native (Human)

Alias

PSAP; ACP; PAP

Source

Human Semen

Species

Human

Appearance

Cloudy, straw colored liquid

Form

Liquid

Enzyme Commission Number

EC 3.1.3.2

Activity

> 200 U/mL (Dimension Clinical Chemistry System)

CAS No.

9001-77-8

Molecular Weight

100 kDa

Purity

Partially Purified

Specificity

Typically > 25 U/mg protein

Unit Definition

One unit will catalyze the hydrolysis of one micromole of thymolphthalein monophosphate to thymolphthalein and phosphate per minute at pH 5.6 and 37°C.

Storage

-20°C

Pathway

Riboflavin metabolism, organism-specific biosystem; Riboflavin metabolism, conserved biosystem

Function

5-nucleotidase activity; acid phosphatase activity; hydrolase activity

Synonyms

Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39

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