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PS 48


Cat No.
COEC-117
Description
PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1, PDK1) activator (Kd = 10.3 μM). Studies have indicated that this compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1). This is a distinct region separate from the ATP binding site.
Applications
A phosphoinositide-dependent protein kinase-1 (PDK1) activator
Form
Solid
CAS No.
1180676-32-7
Molecular Weight
286.76
Synonyms
(Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
Molecular Formula
C17H15ClO2
Solubility
Soluble in DMSO (>20 mg/ml), and ethanol (50 mM).
Boiling Point
~444.1 °C at 760 mmHg (Predicted)
Refractive Index
1.57 (Predicted)
Density
~1.2 g/cm3 (Predicted)
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