(–)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase

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Cat No.

EXWM-0816

Description

This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, produces the direct precursor to etoposide, a potent anticancer drug. It can also act on (–)-deoxypodophyllotoxin with lower efficiency.

Form

Liquid or lyophilized powder

Enzyme Commission Number

EC 1.14.13.214

Storage

Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.

Synonyms

CYP82D61 (gene name)

Reaction

(–)-4'-demethyldeoxypodophyllotoxin + NADPH + H+ + O2 = (–)-4'-demethylepipodophyllotoxin + NADP+ + H2O

Notes

This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.

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Project Description:

For research and industrial use only, not for personal medicinal use.

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