α-Amyloid Precursor Protein Modulator

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Cat No.

COEC-109

Description

α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. α-Amyloid Precursor Protein Modulator displays a marked loss of tumor promoting activity.

Applications

A cell-permeable benzolactam derived PKC activator

Form

Solid

CAS_No

497259-23-1

Molecular Weight

501.55

Purity

≥95%

Synonyms

(2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; PKC Activator V

Molecular Formula

C27H30F3N3O3

Solubility

Soluble in DMSO (50 mg/ml), and methanol (1 mg/ml).

Boiling Point

~728.8° C at 760 mmHg (Predicted)

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Project Description:

Our Products Cannot Be Used As Medicines Directly For Personal Use.

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