(S)-2-Methylproline Hydrochloride

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Cat No.

CEGZ-6990

Description

(S)-2-Methylproline hydrochloride is an α-methylated analogue of the proteinogenic amino acid L-proline, supplied as the hydrochloride salt. The additional methyl group at the α-carbon creates a quaternary center within the pyrrolidine ring.

Applications

Used as a building block in peptide synthesis and medicinal chemistry for the preparation of conformationally constrained, protease-resistant peptide analogues.

Product Overview

α-Methylproline is a strongly conformationally constrained amino acid whose incorporation into peptides stabilizes turn and helical structures and confers high resistance to proteolytic degradation, properties exploited in peptidomimetic and foldamer design.

CAS_No

1508261-86-6

Molecular Weight

165.62

Storage

Store in a tightly closed container in a cool, dry place.

Synonyms

(S)-2-methylpyrrolidine-2-carboxylic acid hydrochloride; α-methyl-L-proline hydrochloride

Molecular Formula

C6H12ClNO2

Notes

For research and development use only.

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Project Description:

For research and industrial use only. Not intended for personal medicinal use. Certain food-grade products are suitable for formulation development in food and related applications.

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